Retinal image analysis

Optic nerve imaging for glaucoma more frequently than once per year is considered not medically necessary. Accepted optic nerve and retinal imaging methods include the following: Confocal laser scanning ophthalmoscopy Nerve fiber layer testing or analysis confocal laser scanning tomography with polarimetry Optical coherence tomography OCT Stereophotogrammetry Aetna considers optic nerve and retinal imaging methods experimental and investigational as a screening test for the following not an all-inclusive list: Decision on the need for surgery Glaucoma and other retinal diseases and for all other indications e.

Retinal image analysis

There are two types of serotonin-accumulating amacrine cell in the rabbit retina Vaney, One of these is Retinal image analysis certainly the A17 cell or the reciprocal amacrine cell of the rod system in the rabbit see previous chapters Fig.

However, in cat retina, a completely different amacrine cell type stains with antibodies against serotonin. Even where serotonin is strongly demonstrated in these amacrine cells in rabbit retina, it is not thought to be the neurotransmitter. Serotonin accumulating amacrine cells in rabbit retina. Adenosine may be a retinal neurotransmitter.

The purine nucleotide, adenosine may be a neurotransmitter or neuromodulator in the mammalian retina.

Autoradiography and immunocytochemistry for adenosine has revealed cell bodies in the amacrine and ganglion cell layers Blazynski and Perez, Probably most of these cells are amacrine cells but some in the ganglion cell layer may be true ganglion cells.

In human retina additional cells that could be bipolar or horizontal cell label too. And the vertical pathway neurotransmitter glutamate can induce adenosine release from [3H]-adenosine preloaded rabbit retina.

Additionally some effects of adenosine on the ERG generated in the retina and on the activity of ganglion cell terminals in the superior colliculus have been recorded and the information points to the strong likelihood that adenosine does play a neurotransmitter role in the vertebrate retina See review by Blazynski and Perez, Adenosine colocalizes with GABA, acetylcholine and serotonin in various retinas.

Much more research is needed in this area. Substance P occurs in an amacrine type and a ganglion cell type. Substance P SP is a neuropeptide belonging to the tachykinin family that include neurokinin A, neuropeptide K and neurokinin B, as well. Substance P is thought to be a neurotransmitter or neuromodulator in the vertebrate retina See Kolb et al.

SP-IR amacrine cells appear to be of a single type in the human retina Fig. They are large-field cells with large cell bodies 16 um diameter lying in normal or displaced positions on either side of the inner plexiform layer IPL.

Their sturdy, spiny and appendage-bearing dendrites stratify in stratum 3 S3 of the IPL, where many overlapping fine dendrites intermingle to form a plexus of stained processes. Long fine dendrites also pass from the dendritic plexus to run in S5 and down to the nerve fibre layer to end as large varicosities at blood vessel walls.

In addition fine processes are emitted from the dendritic plexus that run in S1, and some pass up to the outer plexiform layer OPL to run therein for short distances.

The SP-IR amacrine cell has many similarities to thorny type 2 amacrine cells described in Golgi studies. Its 22 um cell body gives rise to a radiate, sparsely-branched, wide-spreading dendritic tree running in S3. A ganglion cell type in rabbit retina has definitely been proved to contain substance P.

Such ganglion cells almost certainly colocalize a more standard neurotransmitter like glutamate too Brecha et al. Immunostaining with antibodies against somatostatin has revealed a small population of neurons in the ganglion cell layer in the rabbit retina Sagar, They are distributed only in the inferior retina and in the far peripheral circumference of the retina.

However, in the monkey and human retinas these amacrines are more uniformly distributed.Glaucoma Homer Simpson Sign GETOCT. Glaucoma “Homer Simpson Sign” by GETOCT (“donut glaucoma”), normal ganglion cell layer (GCL), left image below, devastated ganglion cell layer (right image).

All Challenges. Here is an overview of all challenges that have been organized within the area of medical image analysis that we are aware of. The retinal vessel analyser (RVA ®) (Imedos, Weimar, Germany) consists of a retinal fundus camera, a CCD video camera, a real-time monitor for electronic online image acquisition, and a PC for overall system control, image analysis and result archiving (Seifert and Vilser, ; Vilser et al., ).

Deep learning algorithms, in particular convolutional networks, have rapidly become a methodology of choice for analyzing medical images. This paper reviews the major deep learning concepts pertinent to medical image analysis and summarizes over contributions to the .

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Retinal image analysis

Jan 01,  · Retinal imaging and image analysis have developed rapidly over the past ten years, and image analysis is starting to play a crucial role in the care of patients with retinal diseases, as well as diseases that manifest in the retina.

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